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Advancements in research





Several new advancements in research are worth highlighting for the month of December. Globally there have been several researches that are potentially very important.

Some of the researchers were involved in corelating treatment for cough with easing up of Parkinson’s Disease. This may surely lead to some more research which may turn out to be beneficial in managing the symptoms.

Some researches focused on identifying a molecule that opposes secretion of dopamine. This discovery could lead to development of medications that can help manage the symptoms better by targeting such a molecule.

Another research focused on development of “smart” glove that can help manage some of the symptoms of Parkinson’s Disease. The device can potentially help in reducing tremors, stiffness and slowness. Another promising study involved using lab-grown stem cells to generate nerve cells that may help in managing the symptoms of Parkinson’s Disease.

Finally, researchers studying the prevalence of Parkinson’s Disease in the US have concluded that the prevalence of disease is rising (50% more than expected).

Following are details about these researches:


1)

Treatment to strengthen cough shows promise for Parkinson’s patients

Parkinson's disease can weaken cough, which is instrumental in clearing aspirated materials from the airpipe. Sensorimotor training for airway protection (smTAP) improved cough-related outcomes more than expiratory muscle strength training (EMST) did. SmTAP uses a specific low-dose, inhaled cough stimulus to cause and improve reflex cough.


Following is the link to the original source:


2)

Scientists’ have identified a key molecule in PD research

Parkinson's disease is a movement disorder that is thought to be brought on by the loss of brain cells that produce dopamine. The striatum, a crucial area of the brain that regulates movement along with reward, motivation, and learning, has long been the subject of scientific conjecture that dopamine is affected by a conflicting dynamic of neuronal signalling. The loss of dopamine-producing cells in Parkinson's disease also primarily affects the striatum. In a recent study, scientists identified adenosine as the neurotransmitter that opposes dopamine for the first time in a clear and conclusive manner. The discovery might quickly reveal fresh possibilities for creating Parkinson's disease-related symptom-treating medications.


Following is the link to the original source



3)

Glove shows potential to ease PD symptoms

Researchers from an esteemed university are developing a glove aimed at alleviating motor symptoms caused by Parkinson’s disease. Although the gadget is still undergoing clinical trial testing, preliminary pilot study findings in about six subjects indicate that it may reduce tremors, slowness, and stiffness.


Following is the link to the original source:


4)

PD prevalence rising

Researchers recently assessed the prevalence of Parkinson's disease by looking at health information from North America. They discovered that the prevalence of Parkinson's disease is 50% higher than expected. The findings may have effects on how PD is diagnosed and treated by healthcare professionals.


Following is the link to the original source:


5)

Radical new therapy for PD will involve stem cell transplants

Stem cells (can transform into different cells) grown in the laboratory and transformed into nerve cells may be potentially used to replace those destroyed by Parkinson's disease. It is hoped that these may possibly stop the spread of debilitating symptoms. Experts say that it is "certainly a promising approach". Scientists expect that their trials will take at least two years to complete.


Following is the link to the original source:




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